Ipamorelin is one of the most selective growth hormone (GH) secretagogues known and a potent agonist of the ghrelin/growth hormone secretagogue receptor. It has been heavily researched in a number of settings and is known to, improve bone health, boost muscle repair and development, stimulate insulin release from the pancreas, and improve bowel motility and gastric function.
Chemical Structure of Ipamorelin
The peptide sequence is Aib–His–D‑2Nal–D‑Phe–Lys–NH₂, with a chemical formula of C₃₈H₄₉N₉O₅ and molecular weight of ~711.9 Da
- Aib (alpha‑aminoisobutyric acid) and 2Nal (2‑naphthylalanine) improve metabolic stability and receptor binding.
- The amidated C-terminal increases resistance to enzymatic degradation.
